Decoding the Mystery of Gene Therapy – An Overview for Nursing (208)

5:00–6:00 pm Thursday, September 5

The decoding of the human genome has provided scientists and researchers a new pathway to developing potential curative therapies for life-threatening or otherwise fatal illnesses. The development of these gene therapies is moving at lightning speed, translating this novel therapy from the bench to the bedside at a record pace. What was once thought of as a highly experimental approach, these therapies are quickly becoming standard of care, as demonstrated by the recent Food and Drug Administration (FDA) approval of several gene therapies, specifically Chimeric Antigen Receptor (CAR) T cell for B cell acute lymphoblastic leukemia and diffuse large B cell lymphoma. These therapies are complex both in their scientific development and, more importantly, in their clinical delivery.

Nursing, with its central role in the patient care delivery model, has a responsibility to understand these therapies. In order to safely and competently deliver gene therapies, nursing providers should be provided education in the science and technology, nursing care implications, and potential adverse effects of the therapy. Gaining a basic understanding of the gene transfer and/or gene-editing processes will provide nursing with the requisite knowledge to build upon as these novel therapies expand in complexity and broadening indications. The presentation will include the science of gene therapy, the current state of gene therapy, in vivo and ex vivo gene therapy, gene editing and other engineered cellular therapy highlighting the differences, and associated nursing care and implications for each. Additional elements of the educational presentation will also detail the multidisciplinary approach required to provide gene therapies and the nursing role in coordinating those activities.

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APHON thanks the Leukemia and Lymphoma Society for their generous support of this event.

Colleen Dansereau, MSN RN CPN
CNE Hours: