12:10 – 12:30 pm Friday, October 29

Paper Presentation: Supportive Care/Quality Improvement — Beyond Words: Expressing Hope Through Creative Art Among Adolescents Who Have Advanced Cancer (216-3)

Purpose/Objectives: This study aimed to (1) conceptualize the essence of hope among adolescents with advanced cancer based on their lived experiences and (2) illustrate how hope evolves through participants’ verbal and artistic depictions of their lived experiences with hope. Four of these drawings and verbatim descriptions are presented as a case series.

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2:15 – 3:15 pm Saturday, October 30

Treating Smarter, Not Harder: Abandoning Intensification and Replacing with Immunotherapy for Patients with Down Syndrome and B-ALL (C234)

coglogoChildren with Down syndrome (DS) have a striking predisposition for developing acute leukemia, with a 40-fold increased risk of developing acute lymphoblastic leukemia (ALL) compared to non-DS patients (Wadhwa et al, 2017). Approximately 3% of children with ALL have DS, and these children have inferior outcomes and higher rates of treatment-related mortality (TRM) and are at greater risk of relapse (Buitenkamp et al., 2014).

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11:30 am – 12:30 pm Saturday, October 30

Clinical Trials in the Children’s Oncology Group: A Case Study Approach (C229)

coglogoClinical trials are essential in the treatment of pediatric and young adult patients with cancer and have resulted in dramatic improvements in cure rates over the years. Because of clinical trials, we are now better able to understand the biology of different types of cancers affecting children and young adults and determine the best treatment options.

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3:30 – 4:30 pm Friday, October 29

Hot Topics in Pediatric Oncology: Updates from the Children’s Oncology Group (C217)

coglogoImprovements in patient care occur when new research findings are moved into practice. The average length of time for this translation, however, is 17 years. Within the past 3 years, the Children’s Oncology Group (COG) has produced 248 publications (about 83 per year).

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5:00 – 6:00 pm Thursday, October 28

Lighting the Way in COG with MATCH: Targeted Therapies in Pediatric CNS Tumors (C211)

coglogoPediatric MATCH (Molecular Analysis for Therapy Choice) is a joint effort between the National Cancer Institute (NCI) and Children’s Oncology Group (COG) matching targeted therapies to specific tumor genomic sequencing in patients with relapsed or refractory solid tumors, non-Hodgkin lymphomas, brain tumors, and histiocytic disorders.

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3:30 – 4:30 pm Friday, October 29

Paper Presentation: Long Term (or Chronic) Supportive Care — Long-term Anticoagulation in Children Utilizing Fondaparinux-A Single Pediatric Center Experience (222-3)

Fondaparinux is a synthetic, subcutaneously administered heparinoid that selectively inhibits activated factor X. Pediatric studies of fondaparinux have shown safety and efficacy profiles for the treatment of venous thromboembolism that was similar to standard pediatric anticoagulants.

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3:30 – 4:30 pm Friday, October 29

Paper Presentation: Long Term (or Chronic) Supportive Care — Individualized Pain Plans in Managing Pain in Patients with Sickle Cell Disease (222-2)

Vaso-occlusive crisis (VOC) is the leading cause of hospital admissions in pediatric patients with sickle cell disease (SCD). Achieving the maximum opioid dose earlier in the admission is associated with shorter lengths of stays, allowing children suffering from SCD to spend less time in the hospital and decreasing their risk for depression and other long-term hospital-associated complications.

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11:50 am – 12:10 pm Friday, October 29

Paper Presentation: Supportive Care/Quality Improvement — Findings from an International Delphi-Study to Develop a Preliminary Core Set of Nursing-Sensitive Quality Indicators for Pediatric Oncology (216-2)

Although nursing-sensitive indicators (NSIs) have been developed to measure factors influencing nursing care quality and patient outcomes in general and in select specialty areas, a core set of NSIs for international pediatric oncology nursing practice does not exist.

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