Immune-Mediated Thrombocytopenia: A Clinical Overview (220)

4:15 pm – 5:15 pm Friday, September 16
Primary immune thrombocytopenia (ITP) is one of the most common hematologic conditions encountered in pediatric hematology and is a diagnosis of exclusion with no specific testing available to confirm the condition. While fairly consistent and typical in presentation, the astute clinician must be able to differentiate between immune and nonimmune etiologies of thrombocytopenia in order to confirm an accurate diagnosis, etiology, and treatment plan while shielding the patient from unnecessary testing and workup.
Pathophysiology, clinical presentation, diagnostic workup, and general management, including pharmacologic management, of primary ITP will be reviewed in detail in the context of current American Society of Hematology (ASH) evidence-based management guidelines with brief discussion regarding secondary ITP etiologies. Management in special clinical circumstances, including surgery and life-threatening bleeding, as well as complications/sequelae, will be also discussed. Finally, case study review will elucidate common and unusual clinical concepts encountered in the management of this common ailment.
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