Germ Cell Tumors: Not All Created Equal (231)

2:15 – 3:15 pm Saturday, October 30

Germ cell tumors (GCTs) are not all created equal. The location of the tumor plays a huge role in the treatment course as well as the outcome. Malignant GCTs (MGCTs) account for about 3% of tumors in children younger than 15 years and about 15% in those age 15–29 years.

Outcomes are good, with an 85% 5-year overall survival (OS) rate. Because of the complex treatment necessary for GCTs, significant side effects can occur in this patient population. New treatments are being evaluated to minimize these effects while still maintaining excellent cure rates. We will discuss the different types of intracranial and extracranial GCTs using several case studies and explain diagnosis, the impact of delayed diagnosis, treatment, and outcomes. Advanced practice nurses are on the front lines of educating families and delivering treatment to patients with GCTs. It is imperative that advanced practice providers have a complete and thorough understanding of MGCTs and how this diverse group of tumors can be so vastly different.