- Shannon Bahrke, Olympian, and CEO, Team Empower Hour
- CNE Hours
Children with Down syndrome (DS) have a striking predisposition for developing acute leukemia, with a 40-fold increased risk of developing acute lymphoblastic leukemia (ALL) compared to non-DS patients (Wadhwa et al, 2017). Approximately 3% of children with ALL have DS, and these children have inferior outcomes and higher rates of treatment-related mortality (TRM) and are at greater risk of relapse (Buitenkamp et al., 2014).
Childhood cancer survivorship care is complex and often requires access to a multidisciplinary team. Signorelli et al. (2017) reported that survivors who are engaged in follow-up care have better health and educational outcomes.
Childhood cancer cure rates have dramatically improved over the last 30 years, reaching approximately 85% (Chow et al., 2020). In total, approximately two-thirds of children diagnosed with cancer annually will survive for more than 5 years after diagnosis (Chow et al., 2020). But cure comes at a cost.