- Amy R. Newman, PhD RN CPNP-PC CPHON®
Lauri Linder, PhD APRN CPHON®
Pamela Hinds, PhD RN FAAN
Julia Challinor, PhD RN MA Ed MSc Medical Anthropology
- CNE Hours
Due to the remarkable improvements in the care of childhood cancer patients, the 5-year survival rate now exceeds 80%. Long-term survivors of childhood and adolescent cancers may experience a range of adverse outcomes that occur due to treatment-specific factors including chemotherapy and radiation therapy.
Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressive and life-threatening syndrome of pathologic immune activation that results in uncontrolled cytokine release and tissue destruction. HLH may be due to an underlying genetic defect or be triggered by infection, malignancy, or autoimmune disorders.
Children, adolescents, and young adults with malignant bone tumors require expert and specialized care beginning at diagnosis and continuing throughout therapy and beyond. Each patient’s treatment plan is likely to include systemic chemotherapy plus radiation and/or surgery to achieve local tumor control.