The Forgotten Organ- Nephrotoxicity and other Kidney Disorders in Childhood Cancer (213)

11:30 am–12:30 pm Friday, September 6

Development of kidney disease is a significant occurrence among children and adolescent patients treated for cancer and require prompt attention, intervention, and follow-up. Renal disease in the pediatric cancer setting is often an underdiagnosed condition, partly due to the emphasis and priority of achieving a cure. Renal disease in the young patient with cancer may result from the malignant process itself or from adverse effects from treatment, including chemotherapy, radiation therapy, surgery, or supportive therapy.

Nephrotoxicity, defined as the ability of an agent to cause functional or structural kidney damage, can be indicative of significant renal impairment and has the potential for profound long-term consequences (McMahon et al., 2018). As cancer therapy continues to advance, renal damage remains a concern for the child and adolescent undergoing treatment and into survivorship. This interactive session will focus on the prevalence and common causes of nephrotoxicity in the young patient with cancer, the presentation, and management of acute kidney injury in this population, as well as chronic kidney disease in survivors of childhood cancer. The discussion will include evaluation and management of impaired renal function and focus on key interventions to prevent and treat kidney disorders in the pediatric oncology setting.

CNE Hours: